The cannabinoid molecule known as Cannabidiol or CBD, found in medicinal cannabis plants, is being recognized for its vast spectrum for the treatment of different chronic conditions and diseases, within which conventional treatments today produce serious adverse effects, leaving thousands of patients without a clear route to treat these pathologies.
New hypotheses and treatment areas arise when investigating clues that nature provides us, today it is known that these cannabinoid molecules have the ability to activate, modulate and even inhibit processes specifically related to our Endocannabinoid System. This capacity is the main reason why it is being analyzed in different models of pathologies.
How is Anxiety Defined?
Anxiety is a physiological or psychological state capable of affecting the complete integrity of a person: behavior, humor, emotions, cognitive processes and it can even cause physical manifestations. Anxiety is usually known as a feeling of worry or fear, which brings with it stress and discomfort.
In normal situations, this feeling of anxiety is a direct natural reaction derived from external stimuli classified as stressful or negative, capable of producing the aforementioned sensations. However, there comes a point where these sensations become uncontrollable, even in extreme cases leading to paranoia.
In recent years, due to the great European economic crisis, cases of anxiety have increased up to 5% more within the Spanish territory.
Anxiety and your Medical Expenses
Within the Spanish territorial framework, it is estimated that about 6 million Spaniards are affected by this disease, finding 8% more cases in women than in men.
A study published in the journal Studies of Applied Economics, analyzed the direct medical costs derived from the care for the treatment of this disease, obtaining the worrying figure of 369 million euros.
Due to these factors, the health system is in a state of transition, changing its approach to find new alternatives for the treatment of this disease.
The exponential growth due to interest in cannabinoid research as novel therapeutic alternatives is presented as a very attractive option, not only for public and private health systems, but also for patients themselves.
Possible Places of Action of CBD in Anxiety
Cannabidiol has a widely demonstrated pharmacological spectrum in recent years, evoking an increase in interest in the investigation of its effectiveness against different current neurological disorders.
Its non-psychotropic effects
The high tolerability presented in patients and animal models Anxiolytic properties dependent on large concentrations in doses, strongly suggest that the use of this phytocannabinoid could be feasible for the treatment or management of neurological disorders such as anxiety.
Therapeutic Relevance of Cannabidiol Against Anxiety
As with any drug or medication, one of the main aspects of the pharmacological effects that must be studied is its safety and tolerance, CBD is very well tolerated in very high dose ranges in human studies, reaching concentrations such as 1500 mg/day by oral route, without reporting effects that affect motor functions, negative effects on mood and other abnormalities at a physiological level.
On the other hand, the anxiolytic effects of CBD are reported in a study conducted by Campos and his team at the Federal University of Minas Gerais, Brazil. Within which they conclude:
“CBD is a safe compound with a wide range of therapeutic applications, including the treatment of psychiatric disorders. These discoveries make this drug an attractive candidate for future clinical trials.”
Other studies conclude that the use of CBD in chronic conditions still requires further investigation, specifically, to determine the appropriate concentrations for CBD to produce its anxiolytic effect.
Conclusions on Medicinal Cannabis (CBD) and its Anxiolytic Effect
Thanks to the results found in different research protocols around the world, there is a growing acceptance within the regulatory and bureaucratic framework for the use of cannabinoid-based therapeutic alternatives such as there are some best cbd gummies for kids.
Much remains to be investigated and known about the potential and complex mechanisms of action within other types of models of conditions and disorders of these molecules. As research is encouraged with larger clinical trials, the bad reputation of this plant and its cannabinoids is also de-stigmatized.